This fact sheet discusses possible health risks from exposure to low levels of vinyl chloride typically found in drinking water wells. If vinyl chloride is detected in your water, contact your local or state health department. Primary exposure to vinyl chloride occurs through inhalation. Under the authority of the Federal Advisory Committee Act (FACA) P.L. Final AEGLs for Vinyl chloride (75-01-4) Exposure Period AEGL-1 AEGL-2 AEGL-3; 10 minutes: 450 ppm : 2800 ppm : 12000 ppm : 30 minutes: 310 ppm : 1600 ppm : 6800 ppm : 60 minutes: 250 ppm : 1200 ppm : 4800 ppm : 4 hours: 140 ppm : 820 ppm : 3400 ppm : 8 hours: 70 ppm : 820 ppm : 3400 ppm Vinyl Chloride 1. Do standards exist for exposure to vinyl chloride? Most vinyl chloride is used to make polyvinyl chloride (PVC) plastic and vinyl products. Vinyl chloride … Portal hypertension, liver fibrosis, and angiosarcoma of the liver (ASL) have been reported among workers exposed to vinyl chloride monomer (VCM) since the 1970s. In 2007, the International Agency for Research on Cancer established the association of VCM with hepatocellular carcinoma (HCC), though o … Prolonged exposure can cause cancer in the liver, brain, blood and lungs. It burns easily. Acute Exposure Guideline Levels. Angiosarcoma attacks the lining of blood vessels, and can occur in any area of the body. 5. Vinyl Chloride 75-01-4 _____ Hazard Summary . It is not stable at high temperatures. Acute (short-term) exposure to high levels of vinyl chloride in air has resulted in central nervous system (CNS) effects, such as … Exposure Sources of Vinyl Chloride. Vinyl chloride is a synthetic, colorless gas. Vinyl chloride is classified as Group 1 carcinogen by the IARC, meaning it is seen as a definite cause of cancer in humans. A copy of the physician's statement shall be provided each employee. (1,2) Assessing Personal Exposure Vinyl chloride can be detected in urine and body tissues, but the tests are not reliable indicators of total exposure. (1,2) Vinyl chloride exposure has been shown to increase the risk of a rare form of liver cancer called angiosarcoma. References: cancer.gov, OSHA, IARC, CDC A statement of each employee's suitability for continued exposure to vinyl chloride including use of protective equipment and respirators, shall be obtained from the examining physician promptly after any examination. PREFACE. Studies in workers who inhale vinyl chloride over many years show an increased risk of … Occupational exposure to vinyl chloride may occur in those workers concerned with the production, use, transport, storage, and disposal of the chemical. The U.S. Environmental Protection Agency has set a maximum contaminant level of 2 ppb of vinyl chloride for public drinking water supplies. 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